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Registro Completo |
Biblioteca(s): |
Embrapa Pecuária Sudeste. |
Data corrente: |
17/11/2020 |
Data da última atualização: |
17/11/2020 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
OKINO, C. H.; BASSETTO, C. C.; GIGLIOTI, R.; SILVA, P. C.; TONELLI, M. F.; MARCONDES, C. R.; OLIVEIRA, H. N. de; OLIVEIRA, M. C. de S. |
Afiliação: |
CINTIA HIROMI OKINO, CPPSE; César Cristiano Bassetto, UNESP; Rodrigo Giglioti, IZ; Pamella Cristini Silva, CNPq; Maria Fernanda Tonelli, FAPESP; CINTIA RIGHETTI MARCONDES, CPPSE; Henrique Nunes de Oliveira, UNESP; MARCIA CRISTINA DE SENA OLIVEIRA, CPPSE. |
Título: |
A polymorphic CD4 epitope related to increased susceptibility to Babesia bovis in Canchim calves. |
Ano de publicação: |
2020 |
Fonte/Imprenta: |
Veterinary Immunology and Immunopathology, v. 230, dec. 2020, 110132. |
Páginas: |
7 p. |
DOI: |
https://doi.org/10.1016/j.vetimm.2020.110132 |
Idioma: |
Inglês |
Conteúdo: |
Different allelic forms of bovine CD4 were previously described in cattle and were also observed in Canchim calves examined in the present experiment. However, the functional relevance of these different CD4 phenotypes has not yet been investigated. CD4 + T helper cells are known to play a central role in immune control against Babesia bovis infection. Thus, our study aimed to compare the profiles of immune cells, specific antibody titers and blood infection levels measured by qPCR (quantitative polymerase chain reaction) in calves naturally infected with B. bovis, phenotyped as CD4- (absence of anti-CD4 staining), CD4 + (intermediate staining) or CD4 ++ (high staining). The CD4 mRNA precursor was also measured in these animals. Calves with the CD4-phenotype showed higher amounts of B. bovis DNA in blood samples, compared to the other CD4 phenotypes. It was also observed that these calves with higher levels of infection had lower amounts of natural killer cells and higher expression of the CD4 gene, which can be interpreted as a compensation for the failure of the altered CD4 receptor to recognize relevant B. bovis epitopes. |
Palavras-Chave: |
Allele; Immunophenotyping; Resistance; T helper cells. |
Thesaurus Nal: |
Calves; Polymorphism. |
Categoria do assunto: |
H Saúde e Patologia |
Marc: |
LEADER 02035naa a2200301 a 4500 001 2126681 005 2020-11-17 008 2020 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.1016/j.vetimm.2020.110132$2DOI 100 1 $aOKINO, C. H. 245 $aA polymorphic CD4 epitope related to increased susceptibility to Babesia bovis in Canchim calves.$h[electronic resource] 260 $c2020 300 $a7 p. 520 $aDifferent allelic forms of bovine CD4 were previously described in cattle and were also observed in Canchim calves examined in the present experiment. However, the functional relevance of these different CD4 phenotypes has not yet been investigated. CD4 + T helper cells are known to play a central role in immune control against Babesia bovis infection. Thus, our study aimed to compare the profiles of immune cells, specific antibody titers and blood infection levels measured by qPCR (quantitative polymerase chain reaction) in calves naturally infected with B. bovis, phenotyped as CD4- (absence of anti-CD4 staining), CD4 + (intermediate staining) or CD4 ++ (high staining). The CD4 mRNA precursor was also measured in these animals. Calves with the CD4-phenotype showed higher amounts of B. bovis DNA in blood samples, compared to the other CD4 phenotypes. It was also observed that these calves with higher levels of infection had lower amounts of natural killer cells and higher expression of the CD4 gene, which can be interpreted as a compensation for the failure of the altered CD4 receptor to recognize relevant B. bovis epitopes. 650 $aCalves 650 $aPolymorphism 653 $aAllele 653 $aImmunophenotyping 653 $aResistance 653 $aT helper cells 700 1 $aBASSETTO, C. C. 700 1 $aGIGLIOTI, R. 700 1 $aSILVA, P. C. 700 1 $aTONELLI, M. F. 700 1 $aMARCONDES, C. R. 700 1 $aOLIVEIRA, H. N. de 700 1 $aOLIVEIRA, M. C. de S. 773 $tVeterinary Immunology and Immunopathology$gv. 230, dec. 2020, 110132.
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Embrapa Pecuária Sudeste (CPPSE) |
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Registro Completo
Biblioteca(s): |
Embrapa Milho e Sorgo. |
Data corrente: |
03/09/1997 |
Data da última atualização: |
13/07/2018 |
Autoria: |
VIANA, P. A.; COSTA, E. F. da. |
Afiliação: |
PAULO AFONSO VIANA, CNPMS. |
Título: |
Efeito da umidade do solo no desempenho de inseticidas utilizados no controle da lagarta-elasmo no milho. |
Ano de publicação: |
1994 |
Fonte/Imprenta: |
In: EMBRAPA. Centro de Nacional de Pesquisa de Milho e Sorgo. Relatório técnico anual do Centro Nacional de Pesquisa de Milho e Sorgo: período 1992-1993. Sete Lagoas, 1994. v. 6, p. 141. |
Idioma: |
Português |
Palavras-Chave: |
Insecticide; Maize; Management; Pest; Pragas. |
Thesagro: |
Controle Químico; Elasmopalpus Lignosellus; Inseticida; Milho; Zea Mays. |
Thesaurus NAL: |
chemical control. |
Categoria do assunto: |
H Saúde e Patologia |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/41338/1/Efeito-umidade-1.pdf
|
Marc: |
LEADER 00859naa a2200253 a 4500 001 1476199 005 2018-07-13 008 1994 bl uuuu u00u1 u #d 100 1 $aVIANA, P. A. 245 $aEfeito da umidade do solo no desempenho de inseticidas utilizados no controle da lagarta-elasmo no milho.$h[electronic resource] 260 $c1994 650 $achemical control 650 $aControle Químico 650 $aElasmopalpus Lignosellus 650 $aInseticida 650 $aMilho 650 $aZea Mays 653 $aInsecticide 653 $aMaize 653 $aManagement 653 $aPest 653 $aPragas 700 1 $aCOSTA, E. F. da 773 $tIn: EMBRAPA. Centro de Nacional de Pesquisa de Milho e Sorgo. Relatório técnico anual do Centro Nacional de Pesquisa de Milho e Sorgo: período 1992-1993. Sete Lagoas, 1994.$gv. 6, p. 141.
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